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转运蛋白SEC62抗体
  • 产品货号:
    BN40570R
  • 中文名称:
    转运蛋白SEC62抗体
  • 英文名称:
    Rabbit anti-SEC62 Polyclonal antibody
  • 货号

    产品规格

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  • BN40570R-100ul

    100ul

    ¥2360.00

    交叉反应:Human,Mouse,Rat(predicted:Dog,Pig,Cow,Horse,Rabbit,Sheep) 推荐应用:WB

  • BN40570R-200ul

    200ul

    ¥3490.00

    交叉反应:Human,Mouse,Rat(predicted:Dog,Pig,Cow,Horse,Rabbit,Sheep) 推荐应用:WB

英文名称SEC62
中文名称转运蛋白SEC62抗体
别    名Dtrp1; FLJ32803; hTP-1; HTP1; Membrane protein SEC62, S.cerevisiae, homolog of; OTTHUMP00000213390; sec62; SEC62 homolog (S. cerevisiae); SEC62_HUMAN; TLOC1; TP-1; Translocation protein 1; Translocation protein sec62.  
研究领域细胞生物  信号转导  转运蛋白  表观遗传学  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat,  (predicted: Dog, Pig, Cow, Horse, Rabbit, Sheep, )
产品应用WB=1:500-2000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量46kDa
细胞定位细胞浆 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human SEC62:251-350/399 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC63 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER. [provided by RefSeq, Jul 2008]

Function:
Required for preprotein translocation.

Subunit:
Part of a complex that contains SEC61, SEC62 and SEC63. Interacts with SEC61B.

Subcellular Location:
Endoplasmic reticulum membrane.

Similarity:
Belongs to the SEC62 family.

SWISS:
Q99442

Gene ID:
7095

Database links:

Entrez Gene: 7095 Human

Entrez Gene: 69276 Mouse

Entrez Gene: 294912 Rat

Omim: 602173 Human

SwissProt: Q99442 Human

SwissProt: Q8BU14 Mouse

Unigene: 592561 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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