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核结合蛋白NUCB1抗体
  • 产品货号:
    BN40564R
  • 中文名称:
    核结合蛋白NUCB1抗体
  • 英文名称:
    Rabbit anti-Nucleobindin 1 Polyclonal antibody
  • 货号

    产品规格

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  • BN40564R-100ul

    100ul

    ¥2360.00

    交叉反应:Human,Mouse,Rat(predicted:Dog,Pig,Cow,Horse,Rabbit,Sheep) 推荐应用:WB,IHC-P,IHC-F,ICC,IF

  • BN40564R-200ul

    200ul

    ¥3490.00

    交叉反应:Human,Mouse,Rat(predicted:Dog,Pig,Cow,Horse,Rabbit,Sheep) 推荐应用:WB,IHC-P,IHC-F,ICC,IF

英文名称Nucleobindin 1
中文名称核结合蛋白NUCB1抗体
别    名CALNUC; FLJ40471; NUC; NUCB 1; NUCB1; NUCB1_HUMAN; Nucleobindin 1; Nucleobindin-1.  
研究领域细胞生物  染色质和核信号  信号转导  结合蛋白  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat,  (predicted: Dog, Pig, Cow, Horse, Rabbit, Sheep, )
产品应用WB=1:500-2000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量54kDa
细胞定位细胞浆 分泌型蛋白 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human Nucleobindin 1:21-120/461 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍This gene encodes a member of a small calcium-binding EF-hand protein family. The encoded protein is thought to have a key role in Golgi calcium homeostasis and Ca(2+)-regulated signal transduction events. [provided by RefSeq, Jun 2010]

Function:
Major calcium-binding protein of the Golgi. May have a role in calcium homeostasis.

Subcellular Location:
Golgi apparatus > cis-Golgi network membrane. Cytoplasm. A small fraction of the protein may be cytoplasmic.

Tissue Specificity:
Expressed both in fetal and adult heart, lung, liver, kidney and brain, and in adult skeletal muscle, placenta and pancreas.

Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.

Similarity:
Belongs to the nucleobindin family.
Contains 2 EF-hand domains.

SWISS:
Q02818

Gene ID:
4924

Database links:

Entrez Gene: 4924 Human

Entrez Gene: 18220 Mouse

Entrez Gene: 84595 Rat

Omim: 601323 Human

SwissProt: Q02818 Human

SwissProt: Q02819 Mouse

SwissProt: Q63083 Rat

Unigene: 631602 Human

Unigene: 258923 Mouse

Unigene: 1492 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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