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BarX2蛋白抗体
  • 产品货号:
    BN40551R
  • 中文名称:
    BarX2蛋白抗体
  • 英文名称:
    Rabbit anti-BarX2 Polyclonal antibody
  • 货号

    产品规格

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  • BN40551R-100ul

    100ul

    ¥2360.00

    交叉反应:Mouse,Rat(predicted:Human,Dog,Cow,Horse,Sheep) 推荐应用:WB,IHC-P,IHC-F,ICC,IF,ELISA

  • BN40551R-200ul

    200ul

    ¥3490.00

    交叉反应:Mouse,Rat(predicted:Human,Dog,Cow,Horse,Sheep) 推荐应用:WB,IHC-P,IHC-F,ICC,IF,ELISA

英文名称BarX2
中文名称BarX2蛋白抗体
别    名BarH like homeobox 2; BarX 2; BARX homeobox; BARX homeobox 2; Barx2; BARX2_HUMAN; Homeobox protein BarH like 2; Homeobox protein BarH-like 2; MGC133368; MGC133369.  
研究领域肿瘤  转录调节因子  细胞粘附分子  结合蛋白  细胞骨架  表观遗传学  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Mouse, Rat,  (predicted: Human, Dog, Cow, Horse, Sheep, )
产品应用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量31kDa
细胞定位细胞核 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human BarX2:81-180/279 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍This gene encodes a member of the homeobox transcription factor family. A highly related protein in mouse has been shown to influence cellular processes that control cell adhesion and remodeling of the actin cytoskeleton in myoblast fusion and chondrogenesis. The encoded protein may also play a role in cancer progression. [provided by RefSeq, Jul 2008]

Function:
Transcription factor. Binds optimally to the DNA consensus sequence 5'-YYTAATGRTTTTY-3'. May control the expression of neural adhesion molecules such as L1 or Ng-CAM during embryonic development of both the central and peripherical nervous system. May be involved in controlling adhesive processes in keratinizing epithelia.

Subcellular Location:
Nucleus.

Tissue Specificity:
Highly expressed in adult salivary gland and at much lower levels in mammary gland, kidney and placenta.

Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.

Similarity:
Belongs to the BAR homeobox family.
Contains 1 homeobox DNA-binding domain.

SWISS:
Q9UMQ3

Gene ID:
8538

Database links:

Entrez Gene: 8538 Human

Entrez Gene: 12023 Mouse

Entrez Gene: 679701 Rat

Omim: 604823 Human

SwissProt: Q9UMQ3 Human

SwissProt: O08686 Mouse

Unigene: 591944 Human

Unigene: 261044 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
















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