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BN40545R-100ul
100ul
¥2360.00
交叉反应：Human(predicted:Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep) 推荐应用：WB
BN40545R-200ul
200ul
¥3490.00
交叉反应：Human(predicted:Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep) 推荐应用：WB
| 英文名称 | ZFR |
| 中文名称 | 锌指RNA结合蛋白抗体 |
| 别 名 | FLJ41312; hZFR; M phase phosphoprotein homolog; M-phase phosphoprotein homolog; zfr; ZFR_HUMAN; zinc finger RNA binding protein; Zinc finger RNA-binding protein. |
| 研究领域 | 肿瘤 细胞凋亡 转录调节因子 结合蛋白 锌指蛋白 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, (predicted: Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, ) |
| 产品应用 | WB=1:500-2000 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 117kDa |
| 细胞定位 | 细胞核 细胞浆 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ZFR:271-370/1074 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| PubMed | PubMed |
| 产品介绍 | ZFR is 1,074 amino acid RNA-binding protein. In human, ZFR is expressed in lung, liver, lymphocytes, heart, pancreas, kidney and placenta, and regulates postimplantation and gastrulation stages of development. Murine ZFR is observed in testis, ovary and brain. With elevated levels of expression during meiosis, ZFR associates with chromosome foci in meiotic cells. ZFR contains 1 DZF domain and localizes in the somatodendritic compartment of hippocampal neurons and colocalizes with STAU2 in cytosolic RNA granules. Knockout of ZFR in mouse embryo prevents the development of some embryonic structures leads to an increase in programmed cell death with a decrease in mitotic index. Function: Involved in postimplantation and gastrulation stages of development. Involved in the nucleocytoplasmic shuttling of STAU2. Binds to DNA and RNA. Subcellular Location: Nucleus. Cytoplasm. Cytoplasmic granule. Chromosome. Associated with chromosome foci in meiotic cells. Localizes in somatodendritic compartment of primary hippocampal neurons. Colocalizes with STAU2 in several cytosolic RNA granules. Tissue Specificity: Expressed in lung, liver, lymphocytes, heart, pancreas, placenta, brain and kidney. Similarity: Contains 1 DZF domain. SWISS: Q96KR1 Gene ID: 51663 Database links: Entrez Gene: 51663 Human Entrez Gene: 22763 Mouse Entrez Gene: 321659 Zebrafish SwissProt: Q96KR1 Human SwissProt: O88532 Mouse SwissProt: Q6PCR6 Zebrafish Unigene: 435231 Human Unigene: 273496 Mouse Unigene: 11634 Rat Unigene: 26724 Zebrafish Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
