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锌指蛋白样1抗体
  • 产品货号:
    BN40544R
  • 中文名称:
    锌指蛋白样1抗体
  • 英文名称:
    Rabbit anti-ZFPL1 Polyclonal antibody
  • 货号

    产品规格

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  • BN40544R-100ul

    100ul

    ¥2360.00

    交叉反应:Human,Mouse,Rat(predicted:Pig,Cow,Horse,Rabbit,Sheep) 推荐应用:IHC-P,IHC-F,ICC,IF,ELISA

  • BN40544R-200ul

    200ul

    ¥3490.00

    交叉反应:Human,Mouse,Rat(predicted:Pig,Cow,Horse,Rabbit,Sheep) 推荐应用:IHC-P,IHC-F,ICC,IF,ELISA

英文名称ZFPL1
中文名称锌指蛋白样1抗体
别    名D11S750; MCG4; MGC 4; ZFPL 1; Zinc finger protein like 1; Zinc finger protein MCG4; zinc-finger protein in MEN1 region.  
研究领域细胞生物  锌指蛋白  表观遗传学  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat,  (predicted: Pig, Cow, Horse, Rabbit, Sheep, )
产品应用ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量34kDa
细胞定位细胞核 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human ZFPL1:31-130/310 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍Zinc finger protein-like 1 is a 310 amino acid single-pass membrane protein with two zinc fingers at the N-terminus, the second of which is likely a RING domain. The RING domain, which is a 40-60 amino acid, cysteine-rich domain that binds two atoms of zinc, plays a key role in the ubiquitination pathway. The presence of zinc finger-like and leucine zipper-like domains in ZFPL1 suggests a role in DNA binding and transcriptional regulation. ZFP1 is widely expressed in the golgi apparatus and is involved in maintaining golgi structure and regulating the rate of cargo transport.

Function:
Required for cis-Golgi integrity and efficient ER to Golgi transport. Involved in the maintenance of the integrity of the cis-Golgi, possibly via its interaction with GOLGA2/GM130.

Subcellular Location:
Golgi Apparatus and Nuclear; Single-pass membrane protein.

SWISS:
O95159

Gene ID:
7542

Database links:

Entrez Gene: 7542 Human

Entrez Gene: 81909 Mouse

Entrez Gene: 84602 Rat

SwissProt: O95159 Human

SwissProt: Q9DB43 Mouse

Unigene: 98170 Human

Unigene: 289471 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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