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甲硫氨酸转运RNA合成酶2抗体
  • 产品货号:
    BN40531R
  • 中文名称:
    甲硫氨酸转运RNA合成酶2抗体
  • 英文名称:
    Rabbit anti-MARS2 Polyclonal antibody
  • 货号

    产品规格

    售价

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  • BN40531R-100ul

    100ul

    ¥2360.00

    交叉反应:Rat(predicted:Human,Mouse,Dog,Cow,Horse) 推荐应用:WB,IHC-P,IHC-F,ICC,IF,ELISA

  • BN40531R-200ul

    200ul

    ¥3490.00

    交叉反应:Rat(predicted:Human,Mouse,Dog,Cow,Horse) 推荐应用:WB,IHC-P,IHC-F,ICC,IF,ELISA

英文名称MARS2
中文名称甲硫氨酸转运RNA合成酶2抗体
别    名mars2; Methionine tRNA ligase 2; Methionine tRNA ligase 2 mitochondrial; Methionine tRNA ligase; Methionine tRNA synthetase 2; Methionine--tRNA ligase; Methionyl tRNA synthetase 2 mitochondrial; Methionyl tRNA synthetase mitochondrial; Methionyl-tRNA synthetase 2; MetRS; mitochondrial; Mitochondrial methionine tRNA ligase; Mitochondrial methionyl tRNA synthetase; Mitochondrial methionyl-tRNA synthetase; MtMetRS; SYMM_HUMAN.  
研究领域细胞生物  神经生物学  信号转导  转运蛋白  表观遗传学  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Rat,  (predicted: Human, Mouse, Dog, Cow, Horse, )
产品应用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量63kDa
细胞定位细胞浆 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human MARS2:31-130/593 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍This gene produces a mitochondrial methionyl-tRNA synthetase protein that is encoded by the nuclear genome and imported to the mitochondrion. This protein likely functions as a monomer and is predicted to localize to the mitochondrial matrix. Mutations in this gene are associated with the autosomal recessive neurodegenerative disease spastic ataxia-3 (SPAX3). [provided by RefSeq, Apr 2014]

DISEASE:
Spastic ataxia 3, autosomal recessive (SPAX3) [MIM:611390]: A neurologic disorder characterized by cerebellar ataxia, ataxic gait, spasticity, and hyperreflexia. Other variable features include dysarthria, dysmetria, mild cognitive impairment, urinary urgency and dystonic positioning. Note: The disease is caused by mutations affecting the gene represented in this entry.

Similarity:
Belongs to the class-I aminoacyl-tRNA synthetase family.

SWISS:
Q96GW9

Gene ID:
92935

Database links:

Entrez Gene: 92935 Human

Omim: 609728 Human

SwissProt: Q96GW9 Human

Unigene: 116602 Human

Unigene: 744330 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.











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