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锌指蛋白24抗体
  • 产品货号:
    BN40523R
  • 中文名称:
    锌指蛋白24抗体
  • 英文名称:
    Rabbit anti-ZNF24 Polyclonal antibody
  • 货号

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  • BN40523R-100ul

    100ul

    ¥2360.00

    交叉反应:Mouse(predicted:Human,Rat,Dog,Pig,Cow,Horse,Sheep,Chimpanzee, Cynomolgus Monkey, Rhesus monkey, Gorilla, Orangutan) 推荐应用:WB,IHC-P,IHC-F,ICC,IF,ELISA

  • BN40523R-200ul

    200ul

    ¥3490.00

    交叉反应:Mouse(predicted:Human,Rat,Dog,Pig,Cow,Horse,Sheep,Chimpanzee, Cynomolgus Monkey, Rhesus monkey, Gorilla, Orangutan) 推荐应用:WB,IHC-P,IHC-F,ICC,IF,ELISA

英文名称ZNF24
中文名称锌指蛋白24抗体
别    名KOX17; Retinoic acid suppression protein A; RSG A; RSGA; Zfp191; Zinc finger and SCAN domain containing protein 3; Zinc finger protein 191; Zinc finger protein 24; Zinc finger protein KOX17; ZNF 24; ZNF191; ZSCAN 3; ZSCAN3.  
研究领域转录调节因子  锌指蛋白  表观遗传学  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Mouse,  (predicted: Human, Rat, Dog, Pig, Cow, Horse, Sheep, Chimpanzee,  Cynomolgus Monkey, Rhesus monkey, Gorilla, Orangutan)
产品应用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量42kDa
细胞定位细胞核 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human ZNF24:201-300/368 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍ZNF24 may function as a transcription factor and acts as a transrepressor in mammalian cell lines. This protein is expressed in many tissues except in heart.

Function:
Transcription factor required for myelination of differentiated oligodendrocytes. Required for the conversion of oligodendrocytes from the premyelinating to the myelinating state. In the developing central nervous system (CNS), involved in the maintenance in the progenitor stage by promoting the cell cycle. Specifically binds to the 5'-TCAT-3' DNA sequence By similarity. Has transcription repressor activity in vitro.

Tissue Specificity:
Expressed in many tissues except in heart.

Post-translational modifications:
Sumoylated.

Similarity:
Belongs to the krueppel C2H2-type zinc-finger protein family.
Contains 4 C2H2-type zinc fingers.
Contains 1 SCAN box domain.

SWISS:
P17028

Gene ID:
7572

Database links:

Entrez Gene: 7572 Human

Entrez Gene: 360204 Rat

Omim: 194534 Human

SwissProt: P17028 Human

SwissProt: Q7TNK3 Rat

Unigene: 514802 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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