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肌动蛋白相关蛋白2/3复合物亚基3抗体
  • 产品货号:
    BN40504R
  • 中文名称:
    肌动蛋白相关蛋白2/3复合物亚基3抗体
  • 英文名称:
    Rabbit anti-p21-ARC Polyclonal antibody
  • 货号

    产品规格

    售价

    备注

  • BN40504R-100ul

    100ul

    ¥2360.00

    交叉反应:Human,Mouse(predicted:Rat,Chicken,Cow,Rabbit,Xenopus laevis) 推荐应用:WB,IHC-P,IHC-F,ICC,IF,ELISA

  • BN40504R-200ul

    200ul

    ¥3490.00

    交叉反应:Human,Mouse(predicted:Rat,Chicken,Cow,Rabbit,Xenopus laevis) 推荐应用:WB,IHC-P,IHC-F,ICC,IF,ELISA

英文名称p21-ARC
中文名称肌动蛋白相关蛋白2/3复合物亚基3抗体
别    名Actin related protein 2/3 complex subunit 3; ARC21; ARPC3_HUMAN; ARP2/3 complex 21 kDa subunit; ARP2/3 protein complex subunit p21; ARPC3.  
研究领域细胞生物  信号转导  细胞骨架  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse,  (predicted: Rat, Chicken, Cow, Rabbit, Xenopus laevis)
产品应用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量20kDa
细胞定位细胞浆 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human p21-ARC:2-100/178 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍This gene encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been conserved through evolution and is implicated in the control of actin polymerization in cells. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2013]

Function:
p21-ARC is part of a complex implicated in the control of actin polymerization in cells. It belongs to a complex composed of ARP2, ARP3, ARPC1, ARPC2, ARPC3, ARPC4 and ARPC5, collectively known as the ARPC3 family. p21-ARC is implicated as an important regulator of growth cone translocation, especially in the CNS (Strasser et al, 2004).

Subunit:
Component of the Arp2/3 complex composed of ARP2, ARP3, ARPC1B/p41-ARC, ARPC2/p34-ARC, ARPC3/p21-ARC, ARPC4/p20-ARC and

Subcellular Location:
Cytoplasm, cytoskeleton. Cell projection.

Similarity:
Belongs to the ARPC3 family.

SWISS:
O15145

Gene ID:
10094

Database links:

Entrez Gene: 10094 Human

Entrez Gene: 56378 Mouse

Entrez Gene: 288669 Rat

Entrez Gene: 415204 Zebrafish

Omim: 604225 Human

SwissProt: O15145 Human

SwissProt: Q9JM76 Mouse

Unigene: 524741 Human

Unigene: 275942 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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