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丝氨酸甲基化酶cSHMT抗体
  • 产品货号：
    BN40500R
  • 中文名称：
    丝氨酸甲基化酶cSHMT抗体
  • 英文名称：
    Rabbit anti-SHMT1 Polyclonal antibody

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    产品规格

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  • BN40500R-100ul

    100ul

    ¥2360.00

    交叉反应：Human(predicted:Mouse,Rat,Rabbit) 推荐应用：WB,IHC-P,IHC-F,ICC,IF,ELISA

  • BN40500R-200ul

    200ul

    ¥3490.00

    交叉反应：Human(predicted:Mouse,Rat,Rabbit) 推荐应用：WB,IHC-P,IHC-F,ICC,IF,ELISA

英文名称SHMT1
中文名称丝氨酸甲基化酶cSHMT抗体
别    名CSHMT; Cytoplasmic serine hydroxymethyltransferase; cytosolic; GLYC_HUMAN; Glycine hydroxymethyltransferase; Serine hydroxymethyltransferase 1 (soluble); Serine hydroxymethyltransferase; Serine hydroxymethyltransferase, cytosolic; Serine methylase; SHMT; Shmt1.  
研究领域细胞生物  信号转导  新陈代谢  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human,  (predicted: Mouse, Rat, Rabbit, )
产品应用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量53kDa
细胞定位细胞浆 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human SHMT1:301-400/483 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍This gene encodes the cytosolic form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one-carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. A pseudogene of this gene is located on the short arm of chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

Function:
Interconversion of serine and glycine.

Subcellular Location:
Cytoplasm.

Similarity:
Belongs to the SHMT family.

SWISS:
P34896

Gene ID:
6470

Database links:

Entrez Gene: 6470 Human

Entrez Gene: 20425 Mouse

Omim: 182144 Human

SwissProt: P34896 Human

SwissProt: P50431 Mouse

Unigene: 513987 Human

Unigene: 636044 Human

Unigene: 364956 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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