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TEFF1蛋白抗体
  • 产品货号:
    BN40491R
  • 中文名称:
    TEFF1蛋白抗体
  • 英文名称:
    Rabbit anti-TEFF1 Polyclonal antibody
  • 货号

    产品规格

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  • BN40491R-100ul

    100ul

    ¥2360.00

    交叉反应:Mouse(predicted:Human,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep) 推荐应用:WB,ELISA

  • BN40491R-200ul

    200ul

    ¥3490.00

    交叉反应:Mouse(predicted:Human,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep) 推荐应用:WB,ELISA

英文名称TEFF1
中文名称TEFF1蛋白抗体
别    名Tomoregulin-1 precursor; C9orf2; C9orf3 TMEFF1; C9orf30 TMEFF1; C9orf30 TMEFF1 fusion protein; Cancer/testis antigen family 120 member 1; CT120.1; H 7365; H7365; MSANTD3-TMEFF1 readthrough; TEFF 1; TEFF1; TEFF1_HUMAN; TMEFF 1; TMEFF1; Tomoregulin-1; TR 1; TR-1; TR1; Transmembrane protein with EGF like and two follistatin like domains 1; Transmembrane protein with EGF-like and one follistatin-like domain.  
研究领域肿瘤  细胞生物  表观遗传学  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Mouse,  (predicted: Human, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
产品应用WB=1:500-2000 ELISA=1:5000-10000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量37kDa
细胞定位细胞膜 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human TEFF1:161-260/380 <Extracellular>
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍This locus represents naturally occurring read-through transcription from the neighboring MSANTD3 (Myb/SANT-like DNA-binding domain containing 3) and TMEFF1 (transmembrane protein with EGF-like and two follistatin-like domains 1) genes. The read-through transcript encodes a fusion protein that shares sequence identity with the products of each individual gene. [provided by RefSeq, Aug 2013]

Function:
May inhibit NODAL and BMP signaling during neural patterning (By similarity). May be a tumor suppressor in brain cancers.

Subcellular Location:
Cell membrane.

Tissue Specificity:
Expressed predominantly in brain, and at lower levels in heart, placenta and skeletal muscle. Down-regulated in brain tumors as compared to control brain tissues.

Similarity:
Belongs to the tomoregulin family.
Contains 1 EGF-like domain.
Contains 2 Kazal-like domains.

SWISS:
Q8IYR6

Gene ID:
8577

Database links:

Entrez Gene: 100526694 Human

Entrez Gene: 8577 Human

Entrez Gene: 230157 Mouse

Entrez Gene: 63845 Rat

Omim: 603421 Human

SwissProt: Q8IYR6 Human

SwissProt: Q6PFE7 Mouse

SwissProt: Q9QYV1 Rat

Unigene: 598100 Human

Unigene: 422686 Mouse

Unigene: 162809 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.












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