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叉头蛋白B2抗体
  • 产品货号:
    BN40471R
  • 中文名称:
    叉头蛋白B2抗体
  • 英文名称:
    Rabbit anti-FOXB2 Polyclonal antibody
  • 货号

    产品规格

    售价

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  • BN40471R-100ul

    100ul

    ¥2360.00

    交叉反应:Human,Mouse(predicted:Rat,Cow,Rabbit) 推荐应用:WB,IHC-P,IHC-F,ICC,IF

  • BN40471R-200ul

    200ul

    ¥3490.00

    交叉反应:Human,Mouse(predicted:Rat,Cow,Rabbit) 推荐应用:WB,IHC-P,IHC-F,ICC,IF

英文名称FOXB2
中文名称叉头蛋白B2抗体
别    名bA159H20.4; Forkhead box B2; Forkhead box protein B2; FOXB 2; Foxb2; FOXB2_HUMAN.  
研究领域细胞生物  信号转导  转录调节因子  表观遗传学  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse,  (predicted: Rat, Cow, Rabbit, )
产品应用WB=1:500-2000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量45kDa
细胞定位细胞核 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human FOXB2:351-432/432 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍The Forkhead-box (FOX) genes comprise a superfamily of at least 43 members that encode proteins which are involved in transcriptional regulation and may be associated with the pathogenesis of various cancers. FOXB1 (forkhead box B1), also known as FKH5 or HFKH-5, and FOXB2 (forkhead box B2) are members of the FOX family and each contain one forkhead DNA-binding domain. Both FOXB1 and FOXB2 localize to the nucleus where they are thought to function as transcription factors that can bind to DNA via their forkhead domains. In mice, defects in the gene encoding FOXB1 are associated with retarded development of the central nervous system (CNS), suggesting that FOXB1 may play a role in CNS organization and function.

Function:
Transcription factor.

Subcellular Location:
Nucleus.

Similarity:
Contains 1 fork-head DNA-binding domain.

SWISS:
Q5VYV0

Gene ID:
442425

Database links:

Entrez Gene: 442425 Human

Entrez Gene: 14240 Mouse

Entrez Gene: 691398 Rat

SwissProt: Q5VYV0 Human

SwissProt: Q64733 Mouse

Unigene: 553843 Human

Unigene: 7971 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.












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