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BN40471R-100ul
100ul
¥2360.00
交叉反应:Human,Mouse(predicted:Rat,Cow,Rabbit) 推荐应用:WB,IHC-P,IHC-F,ICC,IF
BN40471R-200ul
200ul
¥3490.00
交叉反应:Human,Mouse(predicted:Rat,Cow,Rabbit) 推荐应用:WB,IHC-P,IHC-F,ICC,IF
英文名称 | FOXB2 |
中文名称 | 叉头蛋白B2抗体 |
别 名 | bA159H20.4; Forkhead box B2; Forkhead box protein B2; FOXB 2; Foxb2; FOXB2_HUMAN. |
研究领域 | 细胞生物 信号转导 转录调节因子 表观遗传学 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, (predicted: Rat, Cow, Rabbit, ) |
产品应用 | WB=1:500-2000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 45kDa |
细胞定位 | 细胞核 |
性 状 | Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human FOXB2:351-432/432 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
PubMed | PubMed |
产品介绍 | The Forkhead-box (FOX) genes comprise a superfamily of at least 43 members that encode proteins which are involved in transcriptional regulation and may be associated with the pathogenesis of various cancers. FOXB1 (forkhead box B1), also known as FKH5 or HFKH-5, and FOXB2 (forkhead box B2) are members of the FOX family and each contain one forkhead DNA-binding domain. Both FOXB1 and FOXB2 localize to the nucleus where they are thought to function as transcription factors that can bind to DNA via their forkhead domains. In mice, defects in the gene encoding FOXB1 are associated with retarded development of the central nervous system (CNS), suggesting that FOXB1 may play a role in CNS organization and function. Function: Transcription factor. Subcellular Location: Nucleus. Similarity: Contains 1 fork-head DNA-binding domain. SWISS: Q5VYV0 Gene ID: 442425 Database links: Entrez Gene: 442425 Human Entrez Gene: 14240 Mouse SwissProt: Q5VYV0 Human SwissProt: Q64733 Mouse Unigene: 553843 Human Unigene: 7971 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |