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HAUS3蛋白抗体
  • 产品货号：
    BN40457R
  • 中文名称：
    HAUS3蛋白抗体
  • 英文名称：
    Rabbit anti-HAUS3 Polyclonal antibody

  • 货号

    产品规格

    售价

    备注

  • BN40457R-100ul

    100ul

    ¥2360.00

    交叉反应：Human(predicted:Mouse,Rat) 推荐应用：ELISA

  • BN40457R-200ul

    200ul

    ¥3490.00

    交叉反应：Human(predicted:Mouse,Rat) 推荐应用：ELISA

英文名称HAUS3
中文名称HAUS3蛋白抗体
别    名C4orf15; Chromosome 4 open reading frame 15; dgt3; HAUS augmin-like complex subunit 3; haus3; HAUS3_HUMAN; IT1; MGC4701.   
研究领域细胞生物  染色质和核信号  表观遗传学  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human,  (predicted: Mouse, Rat, )
产品应用ELISA=1:5000-10000 Flow-Cyt=0.2ug/test 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量70kDa
细胞定位细胞浆 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human HAUS3:1-100/603 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍HAUS3 is 1 of 8 subunits of the 390-kD human augmin complex, or HAUS complex. The augmin complex was first identified in Drosophila, and its name comes from the Latin verb 'augmentare,' meaning 'to increase.' The augmin complex is a microtubule-binding complex involved in microtubule generation within the mitotic spindle and is vital to mitotic spindle assembly (Goshima et al., 2008 [PubMed 18443220]; Uehara et al., 2009 [PubMed 19369198]).[supplied by OMIM, Nov 2010]

Function:
Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex.

Subunit:
Component of the HAUS augmin-like complex. The complex interacts with the gamma-tubulin ring complex and this interaction is required for spindle assembly.

Subcellular Location:
Cytoplasm, cytoskeleton, centrosome. Cytoplasm, cytoskeleton, spindle. Note=Localizes to interphase centrosomes and to mitotic spindle microtubules.

Similarity:
Belongs to the HAUS3 family.

SWISS:
Q68CZ6

Gene ID:
79441

Database links:

Entrez Gene: 79441 Human

Omim: 613430 Human

SwissProt: Q68CZ6 Human

Unigene: 665869 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.












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