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细胞色素P450 2C18抗体
  • 产品货号:
    BN40444R
  • 中文名称:
    细胞色素P450 2C18抗体
  • 英文名称:
    Rabbit anti-CYP2C18 Polyclonal antibody
  • 货号

    产品规格

    售价

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  • BN40444R-100ul

    100ul

    ¥2360.00

    交叉反应:Human,Mouse(predicted:Rat,Pig,Rabbit,Sheep) 推荐应用:WB,ELISA

  • BN40444R-200ul

    200ul

    ¥3490.00

    交叉反应:Human,Mouse(predicted:Rat,Pig,Rabbit,Sheep) 推荐应用:WB,ELISA

英文名称CYP2C18
中文名称细胞色素P450 2C18抗体
别    名(S) mephenytoin hydroxylase associated cytochrome P450; CPCI; CYP2C 18; CYP2C; CYP2C17; CP2CI_HUMAN; CYPIIC18; Cytochrome P450 2C18; Cytochrome P450 6B/29C; Cytochrome P450 family 2 subfamily C polypeptide 18; Cytochrome P450 subfamily IIC (mephenytoin 4 hydroxylase) polypeptide 17; Cytochrome P450 subfamily IIC (mephenytoin 4 hydroxylase) polypeptide 18; Flavoprotein linked monooxygenase; Microsomal monooxygenase; P450 6B/29C; P450IIC17; Unspecific monooxygenase.  
研究领域细胞生物  信号转导  新陈代谢  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse,  (predicted: Rat, Pig, Rabbit, Sheep, )
产品应用WB=1:500-2000 ELISA=1:5000-10000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量56kDa
细胞定位细胞浆 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human CYP2C18:401-490/490 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum but its specific substrate has not yet been determined. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. An additional gene, CYP2C17, was once thought to exist; however, CYP2C17 is now considered an artefact based on a chimera of CYP2C18 and CYP2C19. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Function:
CYP2C18 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. CYP2C18 oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.

Subcellular Location:
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.

SWISS:
P33260

Gene ID:
1562

Database links:

Entrez Gene: 1562 Human

Omim: 601131 Human

SwissProt: P33260 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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