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细胞色素B5还原酶4抗体
  • 产品货号：
    BN40442R
  • 中文名称：
    细胞色素B5还原酶4抗体
  • 英文名称：
    Rabbit anti-CYB5R4 Polyclonal antibody

  • 货号

    产品规格

    售价

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  • BN40442R-100ul

    100ul

    ¥2360.00

    交叉反应：Human,Mouse,Rat(predicted:Chicken,Dog,Pig,Cow,Horse,Sheep) 推荐应用：WB,IHC-P,IHC-F,ICC,IF,ELISA

  • BN40442R-200ul

    200ul

    ¥3490.00

    交叉反应：Human,Mouse,Rat(predicted:Chicken,Dog,Pig,Cow,Horse,Sheep) 推荐应用：WB,IHC-P,IHC-F,ICC,IF,ELISA

英文名称CYB5R4
中文名称细胞色素B5还原酶4抗体
别    名b5+b5R; b5b5r; C79736; cb5/cb5R; Cb5cb5r; Cyb5r4; Cytochrome b type NAD(P)H oxidoreductase; Cytochrome b5 reductase 4; dJ676J13.1; Flavohemoprotein b5+b5R; Flavohemoprotein b5/b5R; N terminal cytochrome b5 and cytochrome b5 oxidoreductase domain containing protein; N-terminal cytochrome b5 and cytochrome b5 oxidoreductase domain-containing protein; NADPH cytochrome B5 oxidoreductase; NB5R4_HUMAN; NCB5OR; RP4 676J13.1.  
研究领域细胞生物  神经生物学  细胞类型标志物  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat,  (predicted: Chicken, Dog, Pig, Cow, Horse, Sheep, )
产品应用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量59kDa
细胞定位细胞浆 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human CYB5R4:21-120/521 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍NCB5OR is a flavohemoprotein that contains functional domains found in both cytochrome b5 (CYB5A; MIM 613218) and CYB5 reductase (CYB5R3; MIM 613213) (Zhu et al., 1999 [PubMed 10611283]).[supplied by OMIM, Jan 2010]

Function:
NADH-cytochrome b5 reductase involved in endolasmic reticulum stress response pathway. Plays a critical role in protecting pancreatic beta-cells against oxidant stress, possibly by protecting the cell from excess buildup of reactive oxygen species (ROS). Reduces a variety of substrates in vitro, such as cytochrome c, feericyanide and methemoglobin.

Subcellular Location:
Endoplasmic reticulum. Soluble protein.

Tissue Specificity:
Widely expressed.

Similarity:
Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
Contains 1 CS domain.
Contains 1 cytochrome b5 heme-binding domain.
Contains 1 FAD-binding FR-type domain.

SWISS:
Q7L1T6

Gene ID:
51167

Database links:

Entrez Gene: 51167 Human

Omim: 608343 Human

SwissProt: Q7L1T6 Human

Unigene: 5741 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.












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