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碳水化合物磺基转移酶7抗体
  • 产品货号:
    BN40439R
  • 中文名称:
    碳水化合物磺基转移酶7抗体
  • 英文名称:
    Rabbit anti-CHST7 Polyclonal antibody
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    产品规格

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  • BN40439R-100ul

    100ul

    ¥2360.00

    交叉反应:Mouse(predicted:Human,Rat,Dog,Pig,Cow,Rabbit,Sheep) 推荐应用:WB,IHC-P,IHC-F,ICC,IF,ELISA

  • BN40439R-200ul

    200ul

    ¥3490.00

    交叉反应:Mouse(predicted:Human,Rat,Dog,Pig,Cow,Rabbit,Sheep) 推荐应用:WB,IHC-P,IHC-F,ICC,IF,ELISA

英文名称CHST7
中文名称碳水化合物磺基转移酶7抗体
别    名6 O sulfotransferase 5; C6ST 2; C6ST2; Carbohydrate sulfotransferase 7; Chondroitin 6 sulfotransferase 2; CHST 7; CHST7_HUMAN; CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7; Galactose/N acetylglucosamine/N acetylglucosamine 6 O sulfotransferase 5; GlcNAc6ST 4; Gn6st-4; GST 5; N acetylglucosamine 6 O sulfotransferase 1.  
研究领域细胞生物  信号转导  新陈代谢  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Mouse,  (predicted: Human, Rat, Dog, Pig, Cow, Rabbit, Sheep, )
产品应用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量54kDa
细胞定位细胞浆 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human CHST7:101-200/486 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus reducing the number of supercoils and altering the topology of DNA. This enzyme forms a complex with BLM which functions in the regulation of recombination in somatic cells. [provided by RefSeq, Jul 2008]

Function:
CHST7 belongs to the sulfotransferase family. Sulfotransferases generate sulfated glycosaminoglycan (GAG) moities during chondroitin sulfate biosynthesis. They create considerable structural diversity among chondroitin sulfates by transferring sulfate with remarkable specificity for the underlying oligosaccharide substrate. This protein mainly transfers sulfate to N-acetylgalactosamine. The regulated expression of each member of the family may be an important determinant of sulfated GAGs expression and the associated function of chondroitin sulfates as regulators of many biologic processes.

Subcellular Location:
Golgi apparatus membrane; Single-pass type II membrane protein

Tissue Specificity:
Widely expressed. Highly expressed in heart, spleen, liver and ovary. Expressed at lower level in brain, placenta, thyroid, spinal cord and peripheral blood leukocytes. Not expressed in adult skin.

Similarity:
Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.

SWISS:
Q9NS84

Gene ID:
56548

Database links:

Entrez Gene: 56548 Human

Entrez Gene: 540357 Cow

Entrez Gene: 60322 Mouse

Omim: 300375 Human

SwissProt: Q9NS84 Human

SwissProt: Q9EP78 Mouse

Unigene: 129955 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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