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15号染色体开放阅读框58抗体
  • 产品货号:
    BN40416R
  • 中文名称:
    15号染色体开放阅读框58抗体
  • 英文名称:
    Rabbit anti-GDPGP1 Polyclonal antibody
  • 货号

    产品规格

    售价

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  • BN40416R-100ul

    100ul

    ¥2360.00

    交叉反应:Mouse,Rat(predicted:Human,Pig,Horse) 推荐应用:WB,IHC-P,IHC-F,ICC,IF,ELISA

  • BN40416R-200ul

    200ul

    ¥3490.00

    交叉反应:Mouse,Rat(predicted:Human,Pig,Horse) 推荐应用:WB,IHC-P,IHC-F,ICC,IF,ELISA

英文名称GDPGP1
中文名称15号染色体开放阅读框58抗体
别    名C15orf58; Chromosome 15 open reading frame 58; GDP-D-glucose phosphorylase 1; GDP-D-glucose phosphorylase C15orf58; gdpgp1; GDPP1_HUMAN; VTC2.  
研究领域肿瘤  神经生物学  信号转导  新陈代谢  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Mouse, Rat,  (predicted: Human, Pig, Horse, )
产品应用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量42kDa
细胞定位细胞浆 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human GDPGP1/C15orf58:301-385/385 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍Encoding more than 700 genes, chromosome 15 is made up of approximately 106 million base pairs and is about 3% of the human genome. Angelman and Prader-Willi syndromes are associated with loss of function or deletion of genes in the 15q11-q13 region. In the case of Angelman syndrome, this loss is due to inactivity of the maternal 15q11-q13 encoded UBE3A gene in the brain by either chromosomal deletion or mutation. In cases of Prader-Willi syndrome, there is a partial or complete deletion of this region from the paternal copy of chromosome 15. Tay-Sachs disease is a lethal disorder associated with mutations of the HEXA gene, which is encoded by chromosome 15. Marfan syndrome is associated with chromosome 15 through the FBN1 gene. The LOC390637 gene product has been provisionally designated LOC390637 pending further characterization.

Function:
Specific and highly efficient GDP-D-glucose phosphorylase regulating the levels of GDP-D-glucose in cells.

Subcellular Location:
Cytoplasm.

Similarity:
Belongs to the GDPGP1 family.

SWISS:
Q6ZNW5

Gene ID:
390637

Database links:

Entrez Gene: 390637 Human

SwissProt: Q8HXE4 Cynomolgus Monkey

SwissProt: Q6ZNW5 Human

Unigene: 304673 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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