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叉头蛋白F2抗体
  • 产品货号:
    BN40413R
  • 中文名称:
    叉头蛋白F2抗体
  • 英文名称:
    Rabbit anti-FOXF2 Polyclonal antibody
  • 货号

    产品规格

    售价

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  • BN40413R-100ul

    100ul

    ¥2360.00

    交叉反应:Mouse(predicted:Human,Rat,Chicken) 推荐应用:WB,ELISA

  • BN40413R-200ul

    200ul

    ¥3490.00

    交叉反应:Mouse(predicted:Human,Rat,Chicken) 推荐应用:WB,ELISA

英文名称FOXF2
中文名称叉头蛋白F2抗体
别    名FKH L6; FKHL 6; FKHL6; Forkhead box F2; Forkhead box protein F2; Forkhead like 6; Forkhead related activator 2; Forkhead related protein FKHL6; Forkhead related transcription factor 2; FOX F2; FOXF 2; FREAC 2; FREAC2; OTTHUMP00000017863;   
研究领域肿瘤  细胞生物  发育生物学  神经生物学  转录调节因子  表观遗传学  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Mouse,  (predicted: Human, Rat, Chicken, )
产品应用WB=1:500-2000 ELISA=1:5000-10000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量46kDa
细胞定位细胞核 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human FOXF2:65-160/444 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍The FOX family of transcription factors share a common DIUA binding domain termed a winged-helix or forkhead domain. Many FOX proteins play important roles in development, metabolism, cancer and aging. Development of the vertebrate gut is controlled by paracrine crosstalk between the endodermal epithelium and the associated splanchnic mesoderm. FOXF2 (forkhead box F2), also known as FKHL or FREAC2, is expressed in lung and placenta, and has been shown to transcriptionally activate several lung-specific genes. FOXF2 interacts with transcription factors TFIIB and TBP, and may be involved in regulating transcription in embryogenesis and pattern formation in multicellular organisms. FOXF2-deficient mice develop cleft palate and an abnormal tongue, which suggests that FOXF2 may be critical for palatogenesis.

Function:
FOXF2 encodes forkhead box F2, one of many human homologues of the Drosophila melanogaster transcription factor forkhead. FOXF2 is expressed in lung and placenta, and has been shown to transcriptionally activate several lung-specific genes.

Subunit:
Interacts with the transcription factors TBP and TFIIB.

Subcellular Location:
Nuclear.

Similarity:
Contains 1 fork-head DNA-binding domain.

SWISS:
Q12947

Gene ID:
2295

Database links:

Entrez Gene: 2295 Human

Entrez Gene: 14238 Mouse

Omim: 603250 Human

SwissProt: Q12947 Human

SwissProt: O54743 Mouse

Unigene: 484423 Human

Unigene: 125548 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.














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