驱动蛋白家族蛋白13B抗体

产品货号：

BN40363R
中文名称：

驱动蛋白家族蛋白13B抗体
英文名称：

Rabbit anti-KIF13B Polyclonal antibody

货号

产品规格

售价

备注
BN40363R-100ul

100ul

¥2360.00

交叉反应：Mouse,Rat(predicted:Human,Pig,Cow,Horse,Sheep) 推荐应用：WB,IHC-P,IHC-F,ICC,IF,ELISA
BN40363R-200ul

200ul

¥3490.00

交叉反应：Mouse,Rat(predicted:Human,Pig,Cow,Horse,Sheep) 推荐应用：WB,IHC-P,IHC-F,ICC,IF,ELISA

产品描述

英文名称	KIF13B
中文名称	驱动蛋白家族蛋白13B抗体
别名	GAKIN; Guanylate kinase associated kinesin; KI13B_HUMAN; KIAA0639; KIF 13B; KIF13B; Kinesin 13B; Kinesin family member 13B; Kinesin like protein GAKIN; Kinesin like protein KIF13B; Kinesin-like protein GAKIN; Kinesin-like protein KIF13B; OTTHUMP00000225649.
研究领域	细胞生物神经生物学信号转导细胞骨架
抗体来源	Rabbit
克隆类型	Polyclonal
交叉反应	Mouse, Rat, (predicted: Human, Pig, Cow, Horse, Sheep, )
产品应用	WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:200-800 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	203kDa
细胞定位	细胞浆
性状	Liquid
浓度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human KIF13B:351-450/1826
亚型	IgG
纯化方法	affinity purified by Protein A
储存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件	Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed	PubMed
产品介绍	KIF13B is also known as Kinesin-like protein GAKIN or GAKIN and is a 1,826 amino acid protein that is widely expressed in tissues, with highest expression in brain and kidney. KIF13B is localized to the cytoplasm, as well as to the cytoskeleton, and is thought to be a microtubule-dependent motor protein which is able to bind to a variety of proteins in order to traffic them to various locations throughout the cell. KIF13B belongs to the kinesin-like protein family and possesses three domains typical of the kinesin-like protein family, namely an N-terminal motor domain with an ATP-binding motif, an FHA domain which is known to bind diverse cargos and a large stalk domain involved in protein-protein binding. Additionally, KIF13B has a microtubule-interacting sequence which is known as the CAP-Gly domain at its C-terminus. The CAP-Gly domain is highly conserved domain among eukaryotes, and in humans, defects in the CAP-Gly domain are implicated in many diseases affecting the trafficking of vesicles, neuromuscular junctions and lysosome proliferation. Function: May be involved in reorganization of the cortical cytoskeleton. May be functionally important for the intracellular trafficking of MAGUKs and associated protein complexes. Subunit: Binds to DLG1 and DLG4. Interacts (when phosphorylated at Ser-1381 and Ser-1410) with 14-3-3. Subcellular Location: Cytoplasm; cytoskeleton. Tissue Specificity: Ubiquitous. Post-translational modifications: Phosphorylated upon DNA damage, probably by ATM or ATR. Similarity: Belongs to the kinesin-like protein family. Contains 1 CAP-Gly domain. Contains 1 FHA domain. Contains 1 kinesin-motor domain. SWISS: Q9NQT8 Gene ID: 23303 Database links: Entrez Gene: 23303 Human Entrez Gene: 16554 Mouse Entrez Gene: 305967 Rat Omim: 607350 Human SwissProt: Q9NQT8 Human Unigene: 444767 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.