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磷酸化丝氨酸/苏氨酸抗体
  • 产品货号：
    BN40343R
  • 中文名称：
    磷酸化丝氨酸/苏氨酸抗体
  • 英文名称：
    Rabbit anti-Phosphoserine/threonine Polyclonal antibody

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  • BN40343R-100ul

    100ul

    ¥2470.00

    交叉反应：nan(predicted:Phosphoserine/threonine) 推荐应用：IHC-P,IHC-F,ICC,IF

英文名称Phosphoserine/threonine
中文名称磷酸化丝氨酸/苏氨酸抗体
别    名phospho-Ser/Phospho-Thr; pan phospho-Ser/Phospho-Thr; pan-phospho-Ser/Phospho-Thr; pS/pT; p-S/p-T; pSER/pThr; p-SER/p-Thr; p-Sp-T; pan pS/pT; pan p-S/p-T; pan pSER/pThr; pan p-SER/p-Thr; pan p-Sp-T..  
产品类型磷酸化抗体 
研究领域肿瘤  细胞生物  神经生物学  信号转导  激酶和磷酸酶  
抗体来源Rabbit
克隆类型Polyclonal
产品应用IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
细胞定位细胞浆 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthesised phosphopeptide contain Phosphoserine and Phosphothreonine:(p-S)(p-T)-NH2 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍A hallmark of signal transduction pathways is the reversible phosphorylation of serine and threonine residues within specific sequences, or motifs, in target proteins. Specific signaling motifs include not only sequences that are recognized by protein kinases, but also those that are recognized by phosphorylation-dependent binding proteins like 14-3-3. These modular phosphoprotein interacting domains are critical elements in modulating, directing and amplifying intracellular communications. Many critical protein kinases can be regulated by phosphorylation at a specific serine or threonine surrounded by phenylalanine or tyrosine. For example, Akt, an important kinase that regulates cell survival, is activated by phosphorylation at Ser473, a site surrounded by phenylalanine and tyrosine. RSK1, p70 S6 K, and certain PKC isoforms also contain a similar consensus phosphorylation site. Phosphorylation of these sites is required for kinase activity. The Phospho-(Ser/Thr) Phe Antibody is a powerful tool for discovery of new proteins containing this important regulatory motif.

SWISS:
N/A

Gene ID:
N/A

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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