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BN40342R-100ul
100ul
¥2360.00
交叉反应:Mouse,Rat(predicted:Human,Dog,Pig,Cow,Rabbit,Sheep) 推荐应用:IHC-P,IHC-F,ICC,IF,ELISA
BN40342R-200ul
200ul
¥3490.00
交叉反应:Mouse,Rat(predicted:Human,Dog,Pig,Cow,Rabbit,Sheep) 推荐应用:IHC-P,IHC-F,ICC,IF,ELISA
英文名称 | Neurabin 1 |
中文名称 | 神经组织特异性F肌动蛋白结合蛋白抗体 |
别 名 | FLJ20068; KIAA1222; NEB1_HUMAN; Neurabin I; Neurabin-1; Neurabin-I; Neurabin1; Neurabin-1; NeurabinI; Neurabin1; Neural tissue specific F actin binding protein I; Neural tissue-specific F-actin-binding protein I; NRB 1; NRB I; NRB1; NRBI; PPP1R9A; Protein phosphatase 1 regulatory (inhibitor) subunit 9A; Protein phosphatase 1 regulatory subunit 9A. |
研究领域 | 细胞生物 神经生物学 转运蛋白 细胞骨架 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Mouse, Rat, (predicted: Human, Dog, Pig, Cow, Rabbit, Sheep, ) |
产品应用 | ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 123kDa |
细胞定位 | 细胞浆 |
性 状 | Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human Neurabin 1/PPP1R9A:115-165/1098 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
PubMed | PubMed |
产品介绍 | This gene is imprinted, and located in a cluster of imprinted genes on chromosome 7q12. This gene is transcribed in both neuronal and multiple embryonic tissues, and it is maternally expressed mainly in embryonic skeletal muscle tissues and biallelically expressed in other embryonic tissues. The protein encoded by this gene includes a PDZ domain and a sterile alpha motif (SAM). It is a regulatory subunit of protein phosphatase I, and controls actin cytoskeleton reorganization. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009] Function: Binds to actin filaments (F-actin) and shows cross-linking activity. Binds along the sides of the F-actin. May be involved in neurite formation. Inhibits protein phosphatase 1-alpha activity. Subcellular Location: Cytoplasm. Similarity: Contains 1 PDZ (DHR) domain. Contains 1 SAM (sterile alpha motif) domain. SWISS: Q9ULJ8 Gene ID: 55607 Database links: Entrez Gene: 55607 Human Entrez Gene: 243725 Mouse Omim: 602468 Human SwissProt: Q9ULJ8 Human Unigene: 21816 Human Unigene: 10849 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |