首页>>蛋白研究>>抗体>>有脊椎动物脑发育相关蛋白Emx1抗体
有脊椎动物脑发育相关蛋白Emx1抗体
  • 产品货号：
    BN40332R
  • 中文名称：
    有脊椎动物脑发育相关蛋白Emx1抗体
  • 英文名称：
    Rabbit anti-Emx1 Polyclonal antibody

  • 货号

    产品规格

    售价

    备注

  • BN40332R-100ul

    100ul

    ¥2360.00

    交叉反应：Human(predicted:Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep) 推荐应用：WB,IHC-P,IHC-F,ICC,IF,Flow-Cyt,ELISA

  • BN40332R-200ul

    200ul

    ¥3490.00

    交叉反应：Human(predicted:Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep) 推荐应用：WB,IHC-P,IHC-F,ICC,IF,Flow-Cyt,ELISA

英文名称Emx1
中文名称有脊椎动物脑发育相关蛋白Emx1抗体
别    名Empty spiracles homeobox 1; Empty spiracles homolog 1; empty spiracles homolog 1 Drosophila antibodyEmpty spiracles like protein 1; Empty spiracles-like protein 1; EMX1 ; EMX1_HUMAN ; Homeobox protein EMX1.  
研究领域细胞生物  发育生物学  神经生物学  信号转导  干细胞  转录调节因子  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human,  (predicted: Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
产品应用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1ug/Test ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量29kDa
细胞定位细胞核 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human Emx1:201-257/257 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍Emx1 and Emx2 are human homologs to the Drosophila developmental genes empty spiracles expressed in anterior body regions during early Drosophila embryogenesis. Emx1 and Emx2 are homeobox proteins expressed in the developing vertebrate brain. Emx2 is expressed in the dorsal telencephalon and small diencephalic regions, while Emx1 expression is exclusively confined to pyramidal neurons of the dorsal telencephalon. In the embryonic brain, Emx1 is expressed in both proliferating and differentiating neurons while Emx2 is expressed only in proliferating neurons. OTX1 and OTX2 are human homologs of the Drosophila developmental genes orthodenticle. In development, the sequence of expression begins with OTX2 at day 10 post coitum followed by OTX1, Emx2 and finally Emx1. The genes encoding human Emx1 and Emx2 map to chromosomes 2p14-p13 and 10q26.1, respectively.

Function:
Transcription factor, which in cooperation with EMX2, acts to generate the boundary between the roof and archipallium in the developing brain. May function in combinations with OTX1/2 to specify cell fates in the developing central nervous system.

Subcellular Location:
Nucleus.

Tissue Specificity:
Cerebral cortex.

Similarity:
Belongs to the EMX homeobox family.
Contains 1 homeobox DNA-binding domain.

SWISS:
Q04741

Gene ID:
2016

Database links:

Entrez Gene: 2016 Human

Entrez Gene: 13796 Mouse

Entrez Gene: 500235 Rat

Omim: 600034 Human

SwissProt: Q04741 Human

SwissProt: Q04742 Mouse

Unigene: 516090 Human

Unigene: 391473 Mouse

Unigene: 140907 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.














image.png

image.png