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核转录因子SOX8抗体
  • 产品货号：
    BN40316R
  • 中文名称：
    核转录因子SOX8抗体
  • 英文名称：
    Rabbit anti-SOX8 Polyclonal antibody

  • 货号

    产品规格

    售价

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  • BN40316R-100ul

    100ul

    ¥2360.00

    交叉反应：Mouse(predicted:Human,Rat,Cow,Horse) 推荐应用：WB,IHC-P,IHC-F,ICC,IF,ELISA

  • BN40316R-200ul

    200ul

    ¥3490.00

    交叉反应：Mouse(predicted:Human,Rat,Cow,Horse) 推荐应用：WB,IHC-P,IHC-F,ICC,IF,ELISA

英文名称SOX8
中文名称核转录因子SOX8抗体
别    名SOX 8; Sox8; SOX8_HUMAN; SRY (sex determining region Y) box 8; SRY box 8; SRY box containing gene 8; Transcription factor SOX 8; Transcription factor SOX-8; Transcription factor SOX8.  
研究领域神经生物学  转录调节因子  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Mouse,  (predicted: Human, Rat, Cow, Horse, )
产品应用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量47kDa
细胞定位细胞核 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human SOX8:101-200/446 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal.

Function:
May play a role in central nervous system, limb and facial development. May be involved in male sex determination. Binds the consensus motif 5'-[AT][AT]CAA[AT]G-3'.

Subcellular Location:
Nucleus.

Tissue Specificity:
Contains 1 HMG box DNA-binding domain.

Similarity:
Contains 1 HMG box DNA-binding domain.

SWISS:
P57073

Gene ID:
30812

Database links:

Entrez Gene: 30812 Human

Entrez Gene: 20681 Mouse

Entrez Gene: 302993 Rat

Omim: 605923 Human

SwissProt: P57073 Human

SwissProt: Q04886 Mouse

Unigene: 243678 Human

Unigene: 258220 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.















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