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肝癌衍生生长因子/高迁移率族蛋白1样蛋白2抗体
  • 产品货号：
    BN40275R
  • 中文名称：
    肝癌衍生生长因子/高迁移率族蛋白1样蛋白2抗体
  • 英文名称：
    Rabbit anti-HDGF Polyclonal antibody

  • 货号

    产品规格

    售价

    备注

  • BN40275R-100ul

    100ul

    ¥2360.00

    交叉反应：Human(predicted:Mouse,Rat,Pig,Cow,GuineaPig) 推荐应用：IHC-P,IHC-F,ICC,IF,ELISA

  • BN40275R-200ul

    200ul

    ¥3490.00

    交叉反应：Human(predicted:Mouse,Rat,Pig,Cow,GuineaPig) 推荐应用：IHC-P,IHC-F,ICC,IF,ELISA

英文名称HDGF
中文名称肝癌衍生生长因子/高迁移率族蛋白1样蛋白2抗体
别    名HDGF; HDGF_HUMAN; Hepatoma derived growth factor; Hepatoma-derived growth factor; High mobility group protein 1 like 2; High mobility group protein 1-like 2; HMG-1L2; HMG1L2.  
研究领域肿瘤  细胞生物  免疫学  肿瘤细胞生物标志物  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human,  (predicted: Mouse, Rat, Pig, Cow, Guinea Pig, )
产品应用ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量27kDa
细胞定位细胞浆 细胞膜 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human HDGF:81-180/240 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍This gene encodes a member of the hepatoma-derived growth factor family. The encoded protein has mitogenic and DNA-binding activity and may play a role in cellular proliferation and differentiation. This gene was thought initially to be located on chromosome X, however, that location has been determined to correspond to a related pseudogene. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]

Function:
Heparin-binding protein, with mitogenic activity for fibroblasts. Acts as a transcriptional repressor.

Subunit:
Monomer, and domain-swapped homodimer.

Subcellular Location:
Cytoplasm. Nucleus.

Tissue Specificity:
Ubiquitous.

Post-translational modifications:
Sumoylated by SUMO1. Sumoylation prevents binding to chromatin.

Similarity:
Belongs to the HDGF family.
Contains 1 PWWP domain.

SWISS:
P51858

Gene ID:
3068

Database links:

Entrez Gene: 3068 Human

Entrez Gene: 15191 Mouse

Entrez Gene: 114499 Rat

Omim: 600339 Human

SwissProt: P51858 Human

SwissProt: P51859 Mouse

SwissProt: Q8VHK7 Rat

Unigene: 506748 Human

Unigene: 292208 Mouse

Unigene: 860 Rat




Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.


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