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微管蛋白折叠辅助因子E样抗体
  • 产品货号：
    BN40242R
  • 中文名称：
    微管蛋白折叠辅助因子E样抗体
  • 英文名称：
    Rabbit anti-TBCEL Polyclonal antibody

  • 货号

    产品规格

    售价

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  • BN40242R-100ul

    100ul

    ¥2360.00

    交叉反应：Human,Mouse,Rat(predicted:Chicken,Dog,Pig,Cow,Horse,Sheep) 推荐应用：WB,IHC-P,IHC-F,ICC,IF

  • BN40242R-200ul

    200ul

    ¥3490.00

    交叉反应：Human,Mouse,Rat(predicted:Chicken,Dog,Pig,Cow,Horse,Sheep) 推荐应用：WB,IHC-P,IHC-F,ICC,IF

英文名称TBCEL
中文名称微管蛋白折叠辅助因子E样抗体
别    名EL; Leucine-rich repeat-containing protein 35; LRRC35; TBCEL; TBCEL_HUMAN; Tubulin folding cofactor E-like; Tubulin-specific chaperone cofactor E-like protein.  
研究领域细胞生物  信号转导  
抗体来源Rabbit
克隆类型Polyclonal
交叉反应Human, Mouse, Rat,  (predicted: Chicken, Dog, Pig, Cow, Horse, Sheep, )
产品应用WB=1:500-2000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量48kDa
细胞定位细胞浆 
性    状Liquid
浓    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human TBCEL:1-100/424 
亚    型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
产品介绍TBCEL is a 424 amino acid cytoplasmic protein that acts as a regulator of tubulin stability. While abundantly expressed in testis, TBCEL is also present in several tissues at a much lower level. TBCEL contains seven LRR (leucine-rich) repeats, one LRRCT domain and one ubiquitin-like domain. The gene that encodes TBCEL consists of 66,704 bases and maps to human chromosome 11q23.3. Chromosome 11 houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that map to chromosome 11.

Function:
Acts as a regulator of tubulin stability.

Subcellular Location:
Cytoplasm > cytoskeleton.

Tissue Specificity:
Abundantly expressed in testis, but is also present in several tissues at a much lower level.

Similarity:
Contains 7 LRR (leucine-rich) repeats.
Contains 1 LRRCT domain.
Contains 1 ubiquitin-like domain.

SWISS:
Q5QJ74

Gene ID:
219899

Database links:

Entrez Gene: 219899 Human

Omim: 610451 Human

SwissProt: Q5QJ74 Human

Unigene: 504136 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.














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