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BN40224R-100ul
100ul
¥2360.00
交叉反应：Human,Rat(predicted:Mouse,Chicken,Dog,Cow,Horse,GuineaPig) 推荐应用：WB,IHC-P,IHC-F,IF,ELISA
BN40224R-200ul
200ul
¥3490.00
交叉反应：Human,Rat(predicted:Mouse,Chicken,Dog,Cow,Horse,GuineaPig) 推荐应用：WB,IHC-P,IHC-F,IF,ELISA
| 英文名称 | PAG608 |
| 中文名称 | 野生型P53诱导基因1抗体 |
| 别 名 | WIG-1; p53 activated gene 608; PAG608; WIG1; FLJ12296; MGC10613; OTTHUMP00000211906; OTTHUMP00000211907; p53-activated gene 608 protein; PAG 608; WIG 1; Zinc finger matrin-type protein 3; Zinc finger protein WIG-1; ZMAT3_HUMAN; p53 inducible zinc finger protein; p53 target zinc finger protein; PAG 608; WIG 1; WIG 1/PAG608 protein; FLJ31683; WIG1; Zinc finger matrin-type protein 3; WIG1; WIG1/PAG608 protein; Zinc finger matrin type 3; Zinc finger protein WIG 1; Zinc finger protein WIG1; ZMAT 3; ZMAT3. |
| 研究领域 | 肿瘤 细胞生物 染色质和核信号 信号转导 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Rat, (predicted: Mouse, Chicken, Dog, Cow, Horse, Guinea Pig, ) |
| 产品应用 | WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 32kDa |
| 细胞定位 | 细胞核 |
| 性 状 | Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human WIG-1:51-150/289 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| PubMed | PubMed |
| 产品介绍 | This gene encodes a protein containing three zinc finger domains and a nuclear localization signal. The mRNA and the protein of this gene are upregulated by wildtype p53 and overexpression of this gene inhibits tumor cell growth, suggesting that this gene may have a role in the p53-dependent growth regulatory pathway. Alternative splicing of this gene results in two transcript variants encoding two isoforms differing in only one amino acid. Function: Acts as a bona fide target gene of p53/TP53. May play a role in the TP53-dependent growth regulatory pathway. May contribute to TP53-mediated apoptosis by regulation of TP53 expression and translocation to the nucleus and nucleolus. Subunit: Interacts with dsRNA. Subcellular Location: Nucleus. Nucleus, nucleolus. Tissue Specificity: Highly expressed in adult brain, and moderately in adult kidney and testis. Not detected in fetal brain, heart, pancreas, adrenal gland, liver or small intestine. Similarity: Contains 3 matrin-type zinc fingers. SWISS: Q9HA38 Gene ID: 64393 Database links: Entrez Gene: 64393 Human Entrez Gene: 22401 Mouse Omim: 606452 Human SwissProt: Q9HA38 Human SwissProt: O54836 Mouse Unigene: 371609 Human Unigene: 35705 Mouse Unigene: 2925 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. Tissue Specificity : Highly expressed in adult brain, and moderately in adult kidney and testis. Not detected in fetal brain, heart, pancreas, adrenal gland, liver or small intestine. |
